Zaroxolyn and Mykrox - The Metalozane Medicine For congestive heart failure
Metolazone is a diuretic with actions and uses similar to those of the thiazide diuretics even though it does not contain a thiazide ring system. Metalazone is available under brand names Zaroxolyn and Mykrox. It is mainly used to treat congestive heart failure and high blood pressure.
Metolazone is used in the treatment edema, including that associated with heart failure and for hypertension. For edema usual dose is 5 to 10mg, in some cases doses of 20mg or more but nor more than 80mg to be given in 24 hrs.For Hypertension:- 2.5 to 5 mg daily either alone or with other anti hypertensives.
Metolazone aggravates hypersensitivity to other thiazides and sulfonamide derivatives. It is contraindicated in anuria, hepatic coma, severe renal and hepatic dysfunction, refractory hypokalaemia, hyponatraemia, hypercalcaemia, symptomatic hyperuricaemia and Addison’s disease.
Metolazone Drug Interactions: In drugs like Furosemide, ACE inhibitors and glibendamide. Preacaustiosn should be taken while using Metolazone in cases of Diabetes mellitus; gout; electrolyte,disturbances; lupus erythematosus; hepatic and renal impairment;
Side effects on using Metolazone (zaroxolyn ) include dizziness, headache, or heart arrhythmias (palpitations).The Serious, though rare, side effects include aplastic anemia, pancreatitis, agranulocytosis, and angioedema. Metolazone, like other thiazide diuretics, may unmask latent diabetes mellitus or exacerbate gout, especially by interacting with medicines used to treat gout.
Tags: Congestive heart failure, edema, high blood pressure, Hypertension, Metalazone, Mykrox, Zaroxolyn, zaroxolyn side effects