HealthCare

Steve Jobs of Apple is dead. Steve jobs pancreatic cancer
Is it possible that one of the greatest geniuses, inventors and innovators the world has seen - Steve Jobs could have been alive today if only he had been bit more smart when it came to his health? There are currently talks that Steve Jobs relied more on natural and herbal medicines to treat his cancer rather than surgery. Question arises whether it is really true.

Firstly we have to understand the type of cancer Steve Jobs was suffering from. He was suffering from a rare form of pancreatic cancer known as islet-cell neuroendocrine pancreatic cancer. Pancreatic cancer does not show any visible symptoms for as much as 12 years in most cases. By the time it is diagnosed the malignancy would have already grown and spread beyond manageable levels. This is the reason why it has such a high mortality rates. The first year survival rate - the year after which it is diagnosed is 24 percent. The 5 year survival rate is as low as 3%. That means that of 100 persons diagnosed of pancreatic cancer as many as 75 will die at the end of first year and as many as 97 out of 100 persons will die by the fifth year. Pancreatic cancer is the fourth most leading cause of cancer deaths in America. It has highest mortality rates of all the cancers. To aggravate this mortality rate further Steve jobs was suffering from a rare form of pancreatic cancer which has even higher mortality rates.

Steve Jobs' pancreatic cancer was diagnosed in 2003 and he died in 2011. . There only a 3% chance for him to survive beyond 2008. Going by the statistics he definitely lived much longer and gave the world few more great products. Steve Jobs took a number of herbal medicines along with conventional treatment. The news that Steve Jobs relied upon herbal medicines and hence he did not take conventional medical treatment or undergo surgery is totally wrong. No one least of all Steve Jobs would have ever done such a thing. Surgery for cancer is something that is truly daunting and outright scary.

Being such a busy man with the entire world looking towards him in 2003 it was quite possible that he in consultation with his doctors opted for Chemotherapy or radiation and delayed surgery. It is also very common for doctors to administer radiotherapy and chemotherapy on pancreatic cancer patients for a couple of months before doing surgery. This is considered a more effective practice as the chances of relapses are reduced.

Herbal extracts, diet etcetra do have proven anti cancer properties. In fact they are known to be very effective in reducing the risks of cancer. Just as tobacco increases risk of cancer certain herbal extracts can reduce the risk of various types of cancer. But it has to be born in mind that only a doctor and modern medical science can treat cancer effectively. No herb or supplement can treat or cure cancer.

Shilajit as a treatment for reproductive infertility – Try before looking for sperm bank donors. .

Shilajit was used by Indian Yogis and Ayurvedic doctors of India for thousands of years to help childless couples and infertile persons.  Shilajit is perhaps one of the best kept secrets of ancient India.  Modern science and medicine has begun to discover the powers of shilajit in this regard.  Shilajit contains certain types of proteins, amino acids, Dibenzo alpha pyrones, fatty acids, carotenoids, metal ions and Fulvic acid which help in the reproductive function.  Fulvic acid transports the nutrients in shilajit as well as other vitamins and minerals deep into the body cells.  Fulvic acid also flushes out of all the toxns and chemicals that affect the reproductive function.  Shilajit acts on various areas related to reproduction notably male infertility, development and protection of embryo, female sexual dysfunction and libido enhancement.  We will see the ingredients of shilajit and their specific functions in detail.

L-Carnitine an ingredient in shilajit provides an energetic substrate to spermatozoa and it contributes sperm motility.  L Carnitine directly assists in the successful maturation of sperm.

Poly unsaturated fatty acids  PUFA in shilajit give the cell membranes of sperms considerable fluidity to participate in membrane fusion events associated with fertilization.  Another ingredient in Shilajit is Dibenzo alpha pyrones known as DBP.  DBP’s are very essential for sperm health.

The amino acids in shilajit are far more effective than what is available from other sources are supplement extracts.  The amino acids like arginine and lysine are the constituents of sperm chromatine proteins, protomines and histones.

DBP – Chemoproteins ( Dibenzo alpha pyrone chemoproteins) protect against the damage to seminal fluids by reducing the reactive nitrogen species in the sperm.  Reactive nitrogen species act together with reactive oxygen species to damage cells, causing nitrosative stress.  This process destroys the vital sperm cells.  This leads to lower count of sperm in the seminal fluid.  Shilajit thus can very effectively prevent this destruction of vital sperm cells.

The zinc in shilajit is in organic and ionic form.  This is unlike what may be ingested through food or through supplements.  This zinc raises testosterone levels and consequently augments sperm health.

Several detailed studies were done in India on the effect of shilajit on semen quality of adult males.  Seminal analysis was done initially and after 60 days of consuming shilajit.  The results were truly remarkable.

The volume of seminal fluid per ejaculation was 3. 42 ml initially.  It rose to 4. 25 ml after the administration of shilajit.  This was a marketd 24. 27 percentage in seminal volume.

The wet weight of the seminal fluid was 3. 08 grams initially.  It rose to 4. 15 grams after taking shilajit.  This was an increase of 34. 74 percentage. .

Dry weight of the seminal fluid was 317 milli grams initially.  It rose to 394 grams after consuming shilajit.  This was a marked 24. 29 percentage increase.

The fructose content in seminal fluid was 4. 45 milli grams per milli litre initially.  It rose to 5. 18 after consuming shilajit.  This was an increase of 16 percentage.

Amino acid content in sperm is one important factor that determines the survival of spermatozoa in the female genital tract.  The failure of sperm progression in the female genital tract may be due to a decrease of amino acid molecules in semen of infertile patients.  It was also shown in various studies around the world that consumption large amount of amino acid supplements alone did not increase the concentration of amino acid molecules I semen.

Shilajit was found in 2 distinct studies to effectively increase the concentration of amino acids in semen.  The seminal fluids of 2 sets of individuals were studied.  One set was of average age of 60 years and mostly infertile.  The other set was of average age of 30 years.

The amino acid concentration in their seminal fluids was measured initially and after 4 months of taking shilajit.  In older subjects there was an increase of amino acid (total) in semen from 1% to 3%.  In the younger subjects the amino acid concentration increased from 2% to 6%.

Those who wish to enhance their reproductive levels and fertility should consider shilajit as an option.

Shilajit is now fast becoming as the number one energy medicine and life extension supplement.  Those who take shilajit experience varied benefits. Most feel increased in energy and stamina. They feel the stress levels coming down and they hardly have any difficulty in getting deep peaceful sleep and wake up being fully charged with energy.  Most feel a strong immunity to diseases with shilajit. Incidentally a leading Medical Research Centre established under the guidance of by Louis Pasteur in India has conclusively proven that Shilajit in combination with another herb is a effective treatment for HIV positive patients. This combination has been found to be more effective than the anti retroviral drugs used today to treat HIV patients. If such a potent infectious disease can be managed with shilajit one can very well imagine the level of immunity that shilajit can help build.

Ayurvedic medicine is much older than Chinese medicine. They have known about shilajit since thousands of years. Now shilajit is the number one energy medicine in the world. Shilajit’s power comes from it’s potent mineral content and Fulvic acid. Minerals are everything in building up our body. Minerals are needed to build tissues, organs, bones, brain and for that matter the entire body. –You can take any amount of vitamins but without minerals in the body it is not of any use. The place where shilajit comes from is unique.

Himalayan region millions of years ago was home to thousands of different plant life. These plants grow in prolific manner. When they die they decompose during winter they get frozen and in summer time they form a thick black mineral pitch. In Russia shilajit is called as Mumiyo.

Shilajit is now fast becoming as the number one energy and life extension supplement.                Those who take shilajit experience varied benefits. Most feel increased in energy and stamina. They feel the stress levels coming down and they hardly have any difficulty in getting deep peaceful sleep and wake up being fully charged with energy.  Most feel a strong immunity to diseases with shilajit. Incidentally a leading Medical Research Centre established under the guidance of by Louis Pasteur in India has conclusively proven that Shilajit in combination with another herb is a effective treatment for HIV positive patients. This combination has been found to be more effective than the anti retroviral drugs used today to treat HIV patients. If such a potent infectious disease can be managed with shilajit one can very well imagine the level of immunity that shilajit can help build.

Ayurvedic medicine is much older than Chinese medicine. They have known about shilajit since thousands of years. Now shilajit is the number one energy medicine in the world. Shilajit’s power comes from it’s potent mineral content and Fulvic acid. Minerals are everything in building up our body. Minerals are needed to build tissues, organs, bones, brain and for that matter the entire body. –You can take any amount of vitamins but without minerals in the body it is not of any use. The place where shilajit comes from is unique.

Himalayan region millions of years ago was home to thousands of different plant life. These plants grow in prolific manner. When they die they decompose during winter they get frozen and in summer time they form a thick black mineral pitch. In Russia shilajit is called as Mumiyo.

Shilajit is an amazing substance made of decomposed plant material oozing out of rocks in Himalayan Mountains. Natives found about Shilajit hundreds of years ago after observing the monkeys in Himalayan mountains. They observed the monkeys climbing up the rocks and eating a substance oozing out of the rocks. The natives also observed that the monkeys there had a very long life, full of energy and lot of offspring. They realized that this was actually due the substance from the rocks that the monkeys were eating. Shilajit is the mineral pitch. It’s very name in Sanskrit means “rock like”. Shilajit is estimated to be millions of years old. It is the decomposed organic matter from the rich vegetation in Himalayan Mountains which are compressed in the rocks over these millions of years. It has been now found scientifically that this process of compression of plant vegetation in the altitude and climatic conditions of Himalayan Mountains produced a truly magnificent substance.

Shilajit contains some 85 minerals in organic bio available form. It is important that minerals are in ionic and bio available form. The mineral supplements that we normally get are the colloidal minerals. The inorganic minerals are ground, made into fine powder and extruded as tablets, filled in capsules are mixed in syrups and sold over the counter. These minerals are not easily absorbed by the body cells and most of it is deposited in organs and tissues causing more harm in the long run. This is the major difference between the minerals found in shilajit and the ones found ion conventional minerals supplements.  More importantly shilait also contains a type of humic acid known as fulvic acid which is formed due this millions of years of compression. Fulvic acid is one of the most powerful electrolytes in the planet and is increasing being recognized as a miracle supplement. Fulvic acid in shilajit makes your cells more permeable to minerals.

Shilajit by itself has 85 plus minerals in highly available ionic form and it also has fulvic acid in it. Thus benefits of shilajit are compounded several times. Shilajit ensures complete absorption of vital minerals deep into the cells. Fulvic acid also makes the cell walls more permeable and flushes out all the toxins and heavy metals from deep within the cells. Shilajit effectively re mineralizes your body. In Ayurveda the traditional Indian medical system Shilajit is known as the “amrit” or  the elixir that extends life. Ayurveda considers Shilajit as a potent adaptogen and a destroyer of weakness.

Basically the power of shilajit comes from its ability to re mineralize the body. It’s power to supply the body cells of all the essential minerals which is normally not possible due to the thick cell walls. Most of the body imbalances and ailments can be traced to mineral deficiency. This mineral deficiency cannot be treated by taking other mineral supplements or even by taking mineral rich food.

Shilajit is traditionally taken in India along with cow’s milk as this is the main source of protein and fat in the predominantly vegetarian Indian diet. But for westerners who have wide range of source of proteins and fats this can be taken with water juice if milk is not tolerated. Soya milk and fat free milk too are good options. Shilajit can be taken on a daily basis. Shilajit is an adaptogen and will help fight stress continuously. It will rejuvenate and rebuild the body on a level that one could previously only dream, of.

Shilajit means destroyer of weakness. It comes from Ayurvedic system of medicine of india and it is estimated that shilajit is continually being used by humans for well over 10,000 years. It is in fact and perhaps the very basis of Ayurvedic system of medicine. It is a mineral pitch found in Himalayan mountains trapped in the rocks. Thousands of years ago great yogis and sages of Himalayan Mountains India found animals eating shilajit and leading a very healthy and prolonged life. So the yogis thought that there is something magical about shilajit and followed it in their diet.  Shilait is rich in minerals and by some estimation contains over 85 trace minerals and fulvic acid. Fulvic acid is a neutralizer of toxins. It is a neutralizer of pesticides and bad estrogens.

Fulvic acid is one of the powerful internal cleansers and is naturally present in shilajit. Humic acid is also present in this susbtance which help in detoxification. These help in the assimilation of minerals that is consumed as a part of normal diet as well the minerals found in shilajit itself. Shilajit has a smooth flavor and hence can be mixed with any food items and beverages. Mixing shilajit with soya milk, cow’s milk , chocolate or juice is very ideal. Shilajit is not really a herb and not completely a supplement. It is somewhat in between. It is a natural mineral pitch that is found in natural cracks of rocks in the high altitudes of Himalayan Mountains. Shilajit is something you should take and see if it works for you.  Many who have been hesitant in the past about this wonder substance have become lifelong votaries and proponents of shilajit.

A Mumbai-based scientist's path-breaking research on rogue proteins in human brain that cause Alzheimer's has brought new hope in the global quest for finding a treatment for the degenerative disorder previously thought to be incurable.

Dr Sudipta Maiti, a professor at the Department of Chemical Sciences, TATA Institute of Fundamental Research (TIFR), and his team have found that it is possible to reverse the behaviour of Amyloid Beta protiens that cause Alzheimer's when they depart from their prescribed function of aiding human memory and cognitive behavior. These renegades join hands with other similarly misbehaving protiens, and together they attack brain cells impairing speech, judgement, memory, perception and behaviour.

Dr Maiti's research showed that when these gangs of bad-boy Amyloid Beta protiens are separated from each other, they return to their original form and resume originally prescribed functions, mainly related to aiding human memory and cognitive behavior. So far it was believed that the Amyloid Beta oligomers - science jargon for gangs of bad-boy protiens - were a stable bunch and did not return to their normal state. With Dr Maiti's research, this thinking is bound to change. Alzheimer's Disease International, a federation of non-profit organizations promoting awareness about the disease, has estimated that as of 2010, there were 35.6 million people with dementia worldwide. By 2050, it is projected that this figure will have increased to over 115 million. Since Alzheimer's is an old-age disease and India's life expectancy has been rising rapidly, one is likely to hear more about it in the coming years.

Dr Maiti's team demonstrated the mob mentality of Amyloid Beta protiens gone bad by creating Alzheimer's disease in a test tube. They placed monomers (single units) of Amyloid Beta in a water-based solution at a normal concentration of 100 nm (nanomolar), mimicking the human brain fluid (cerebro spinal fluid). "When we increased the concentration of the fluid above normal, we observed that the Amyloid Beta protein started forming oligomers (multiple units). These oligomers, together, were toxic enough to cause Alzheimer's," he said. However, when the concentration of artificial brain fluid was lowered to normal again, Amyloid Beta oligomers split back into individual units, lost their toxicity and, in fact, returned to performing their original assigned tasks.

"We were able to reverse the Alzheimer's disease in the test tube. We discovered that after seven days of lowering the concentration of the brain fluid, the oligomers became unstable and broke out from the group to form harmless monomers of the protein found in healthy brains," Maiti said.

Shilajit & Withania Somnifera combination  has been proven to be extremely beneficial in brain degenerative ailments of Alzheimer's   Visit  www.rudramani.com

The small biotechnology company and the Swiss pharmaceutical giant will develop Evotec has signed a new agreement with partner Roche to develop a compound with potential in Alzheimer's disease, replacing an antidepressant programme which was dropped in May.

The German biotechnology company said it will receive $10 million in upfront licensing fees as a result of Roche's decision to collaborate on the development of the new compound, a monoamine oxidase type B inhibitor codenamed EVT-302.

The agreement could also see Evotec receive development and milestone payments up to $820m and tiered double-digit royalties on sales should the drug candidate reach the market. Proof-of-concept clinical trials are scheduled to start next year.

As a result of the latest deal Evotec has raised its revenue forecasts for 2011 to 77-79 million euros from an earlier prediction of 70-72 million euros. MAO-B inhibitors are thought to work in Alzheimer's disease by blocking the breakdown of neurotransmitters and interrupting the formation of reactive oxygen species (ROS) involved in the inflammation and degeneration of neurons which are the hallmark of Alzheimer's disease.

"For these reasons, the selective MAO-B inhibitor is targeted to treat AD symptoms and potentially slow disease progression," said Evotec in a statement.

EVT-302 joins other programmes at Roche targeting two other key characteristics of Alzheimer's disease, namely amyloid plaques and tau proteins.

The Swiss drugmaker's lead programmes are gantenerumab and RG7412, both of which are monoclonal antibodies targeting the amyloid pathway which are currently in Phase II trials.

SHILAJIT for Alzheimer's disease http://www.rudramani.com and commercialize Evotec's MAO-B inhibitor in patients with Alzheimer's disease.

Under the terms of the agreement, Roche will pay Evotec an upfront fee of $10 million, which analysts view as the main reason for the steep share gains.

Evotec could then receive further development and commercial milestone payments of up to $820 million, as well as tiered double-digit royalties on sales. Roche will initiate studies in 2012 to demonstrate proof of concept and will be responsible for all clinical development, manufacturing and commercialization activities.

Evotec, which generated revenue of EUR55.3 million in 2010, has been continuing to seek alliances with large pharmaceutical companies due to the risks and high costs involved in developing new drugs.

"This shift in strategy away from the cost-intensive own research is paying off," said an analyst, who wished to remain anonymous. "Roche is a major partner and Alzheimer's a widespread disease in the center of research," he said.

At 1000 GMT, Evotec shares traded up as much as 16% at EUR2.14, while the TecDAX was up 0.2%.

Alzheimer's disease is the most common cause of dementia and, according to the World Health Organization, affects around 35 million people worldwide.

Shilajit & Withania Somnifera combination  has been proven to be extremely beneficial in brain degenerative ailments of Alzheimer's   Visit  www.rudramani.com

Phyto nutrients have excellent pharmacological actions. They are known to boost immunity, heal diseases and promote well being. Phyto nutrients are being discovered in wide range of foods that are already being valued for their high nutrition content. One such high value food is soybean. The isoflavones in this superfood have been found to protect against any types of cancer moist importantly the breast cancer.   Genistein is that specific phyto nutrient in soybeans that has this beneficial anti cancer property.

Genistein is a phyto estrogen and can plug the receptors for real estrogens which cause breast cancer. Studies have shown that soy based diet increases menstrual cycle by about 2 days. A longer menstrual cycle means less exposure to estrogens. This may be one of the reasons why Japanese and Chinese women who consume large amount of soy based products have much lower incidence of breast cancer. Genistein may also reduce menopausal symptoms and prevent osteoporosis.